image
Tirrell Group

Guilhem De Hoe, Ph.D.

  • Postdoctoral Researcher (Alumni 2021)
    Current: Postdoctoral Research Fellow, Sustainable Materials Innovation Hub, UK

  • Contact: dehoe@uchicago.edu
  • Office Location:
    241 Materials Science Division, Argonne National Laboratory

Guilhem was born in Paris, France and raised in the California bay area. He obtained his B.S. in chemistry at California Polytechnic State University, San Luis Obispo CA. While there, he worked with Prof. Philip Costanzo and prepared polymer surfactants for the dispersion of carbon nanotubes in aqueous media; this included an internship at Sandia National Laboratories in Livermore, CA. He then joined a doctoral program in chemistry at the University of Minnesota and joined the research group of Prof. Marc Hillmyer. Guilhem's doctoral work centered on the design, synthesis, and characterization of sustainable cross-linked plastics as well as their enzymatic degradation; the latter involved a long-term visit to work in the labs of Prof. Dr. Kris McNeill and Dr. Michael Sander at ETH Zurich in Switzerland. After obtaining his Ph.D., Guilhem joined the group of Prof. Matthew Tirrell and works primarily at Argonne National Laboratory.

Solution behavior of polyzwitterions and fundamental relationships between it and antifouling performance.

Harnessing the therapeutic potential of biomacromolecules through intracellular delivery of nucleic acids, peptides and proteins

Yu Tian, Matthew V. Tirrell, James L. LaBelle. "Harnessing the therapeutic potential of biomacromolecules through intracellular delivery of nucleic acids, peptides and proteins". Advanced Healthcare Materials, 2022.

Targeted polyelectrolyte complex micelles treat vascular complications in vivo

Zhengjie Zhou, Chih-Fan Yeh, Michael Mellas, Myung-Jin Oh, Jiayu Zhu, Jin Li, Ru-Ting Huang, Devin L Harrison, Tzu-Pin Shentu, David Wu, Michael Lueckheide, Lauryn Carver, Eun Ji Chung, Lorraine Leon, Kai-Chien Yang, Matthew V Tirrell, Yun Fang. "Targeted polyelectrolyte complex micelles treat vascular complications in vivo", PNAS.

Protein primary structure correlates with calcium oxalate stone matrix preference

Yu Tian, Matthew Tirrell, Carley Davis, Jeffrey A Wesson. "Protein primary structure correlates with calcium oxalate stone matrix preference". Plos One, 2021, e0257515.

Polyampholyte physics: Liquid–liquid phase separation and biological condensates

Dinic, Jelena, Amanda B. Marciel, and Matthew V. Tirrell. "Polyampholyte physics: Liquid–liquid phase separation and biological condensates." Current opinion in colloid & interface science 54 (2021): 101457.

Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity

"Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity". ACS Cent. Sci. 2021, 7, 8, 1368-1380.

Advances in the Structural Design of Polyelectrolyte Complex Micelles

Alexander E. Marras, Jeffrey M. Ting, Kaden C. Stevens, and Matthew V. Tirrell. "Advances in the Structural Design of Polyelectrolyte Complex Micelles". J. Phys. Chem. B, 2021, 125, 26, 7076-7089.

Physical Property Scaling Relationships for Polyelectrolyte Complex Micelles

Alexander E. Marras, Trinity R. Campagna, Jeffrey R. Vieregg, and Matthew V. Tirrell. "Physical Property Scaling Relationships for Polyelectrolyte Complex Micelles". Macromolecules, 2021, 54, 13, 6585-6594.

Effect of Solvent Quality on the Phase Behavior of Polyelectrolyte Complexes

Lu Li, Artem M Rumyantsev, Samanvaya Srivastava, Siqi Meng, Juan J de Pablo, Matthew V Tirrell. "Effect of Solvent Quality on the Phase Behavior of Polyelectrolyte Complexes", Macromolecules, 2020.

View All Publications