Synthetic biology research merges the principles of design and chemistry with living systems to build innovative biological tools from the molecular level up. Our engineers construct custom genetic circuits, program synthetic cells with extreme resilience, and engineer living cellular sensors capable of navigating the body to detect and treat complex diseases in real time.

Faculty

Juan Mendoza

Juan Mendoza

Assistant Professor of Molecular Engineering, Senior Advisor to the Dean for Diversity & Inclusion, UChicago Pritzker School of Molecular Engineering
Research Topics
Immunoengineering and Bioengineering
Research and Scholarly Interests
Protein Engineering
Structural Biology
Computational Biology
Immunology
Cell Signaling
Research Groups
Mendoza Group
Mark Mimee

Mark Mimee

Assistant Professor of Molecular Engineering, UChicago Pritzker School of Molecular Engineering and the Department of Microbiology
Research Topics
Immunoengineering and Bioengineering
Research and Scholarly Interests
Synthetic Biology
Microbiome
Host-Pathogen Interactions
Antimicrobials
Biosensors
Research Groups
Mimee Lab
Rama Ranganathan

Rama Ranganathan

Joseph Regenstein Professor, Department of Biochemistry and Molecular Biology, UChicago Pritzker School of Molecular Engineering, and the College
Research Topics
Immunoengineering and Bioengineering
Research and Scholarly Interests
Bioengineering
Protein Folding
Research Groups
Ranganathan Lab
Milos Simic

Milos Simic

Neubauer Family Assistant Professor of Molecular Engineering, UChicago Pritzker School of Molecular Engineering
Research Topics
Immunoengineering and Bioengineering
Research and Scholarly Interests
Cell Engineering
Synthetic Biology
Neuroinflammation
Neurodegeneration
Brain-Targeted Therapies
Research Groups
The Simic Lab
Savas Tay

Savas Tay

Professor of Molecular Engineering, UChicago Pritzker School of Molecular Engineering
Research Topics
Immunoengineering and Bioengineering
Research and Scholarly Interests
Immune Signaling
Single-Cell Analysis
Microfluidics
Infectious Diseases
Microbiome
Research Groups
Tay Lab